Endocrinology Case 9 Review Questions

1 . Which one of the following is correct regarding beta-cell neoplasia in dogs?
Insulinomas are usually not maliginant
Metastasis is to lung
Nearly 90 percent of dogs die within 6 months of diagnosis
All dogs with malignant tumors die within 2 years
Tumors are usually detectable with ultrasound

2.All of the following are correct regarding the clinical signs of hypoglycemia EXCEPT?
Signs are adrenergic and neurological
Weakness is caused by muscle glucopenia
Seizures are caused by neuronal glucopenia
Nervousnes, facial twitching, and pupillary dilatation are early signs
Carbohydrate reserve in neurons is very limited.

3.All of the following are documented causes of hypoglycemia EXCEPT?
Severe hepatic necrosis
Cortisol deficiency
Insulin excess
Uremia
Hyperthyroidism

4.All of the following drugs either inhibit release or synthesis of insulin EXCEPT?
Diazoxide
Somatostatin
Propranolol
Prednisone
Phenytoin

5.Regarding the surgical management of bet-cell neoplasia, which one of the following is correct?
Turmors are visulized in less than 50% of cases
Tumors occur most commonly in the central region of the pancreas
The most common sites for metastasis are regional lymph nodes and liver
Pancreatic insufficiency is a common complication of surgery
Methylene blue is a safe way to identify tumors in the pancreas.

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