Endocrinology Case 8 Review Questions

1 . All of the following are documented causes of hypercalcemia except?
Perianal gland carcinoma
Chronic granulomatosis disease
Lymphosarcoma
Hyperadrenocorticism
Renal failure

2.Which of the following statements is NOT correct regarding the hypercalcemia of malignancy?
most common cause is lymphosarcoma
tumor produces PTHrp
refractory to prednisone therapy
PTH levels are decreased
Maybe associated with increased serum globulins

3.Regarding the treatment of hypercalcemia, which statement is NOT correct?
Saline diuresis competes with calcium tubular resorption
Furosemide inhibits calcium resorption in Henle's loop
Bicarbonate therapy shifts protein bound calcium to the ionized state.
Calcitonin reduces osteoclast activity and is partially effective in some cases.
Glucocorticoids reduce bone resorption, inhibit GI calcium absorption, and promote the renal excretion of calcium.

4.Hypercalcemia in chronic renal failure may be associated with all of the following except?
decreased renal excretion of calcium
increased concentrations of PTH
incidence of 40-50%
hyperphosphatemia
calcium in the range of 11.0-12.5 mg/dl

5.In nutritional secondary hyperparathyroidism, all of the following are correct except?
serum calcium levels are usually low normal
PTH levels are increased
Chief cell hyperplasia is present
hyperphosphaturia is present
serum phophate levels are increased

6.All of the following are associated with cholecalciferol rodenticide toxicosis except?
hypercalcemia
hyperphosphatemia
hematemesis
renal failure
radiographically detectable demineralization of bone

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