Endocrinology Case 3

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1. Data Base Collection

Signalment: Feline domestic shorthair,10 years old, m/c

History: One year ago cat developed miliary dermatitis and was treated with megesterol acetate at 5 mg orally twice a week for 6 months. Therapy was discontinued about 3 weeks ago. Three months ago cat began to lose weight. During the past 60 days cat has increased thirst and the litter box is wetter than normal. His appetite has increased and he passes large amounts of bulky feces. There is no vomiting, sneezing or coughing. Cat is vaccinated yearly for panleukopenia and upper respiratory viruses and every 3 years for rabies.

Physical Examination: T. 103 F, HR 180-220, RR 50, and weight is 6 pounds. Cat is restless and uneasy. His coat is dull and ungroomed. Lymph nodes are normal. Thoracic auscultation reveals a definite gallop rhythm. Abdominal palpation reveals mild hepatomegaly and the mammary glands are enlarged and non-painful. Cervical palpation is negative.

Diagnostic Plan: Using the POVMR format, identify the problems and formulate a diagnostic plan for this case.

2. Problem Identification

A. List the problems you have observed.

No.

     Problem

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2 .

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B. Of the problems you have identified, which is (are) the most important to manage?

3. Plan Formulation

A. DX: List ruleouts for the problems you identified in Step 2.

Problem
No.

     Ruleout(s)

1 .

2 .

3 .

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10 .

B. List those diagnostic procedures that will be most cost-effective.

1 .  2 . 

3 .  4 . 

5 .  6 . 

7 .  8 . 

9 .  10 . 

4. Assessment & Follow-up

Analyze the initial database results.

Hematology: RBC Morphology:
Test Value Unit
Point your
mouse here
to view Hematology Norms
 
Test Value
WBC 15500 x 103 /mm3  Normal normal
RBC 5.8 x 106 /mm3  Rouleaux  
HGB 12 gr/dl Polychrome  
PCV 36 % Aniso  
MCV 42 fl Poik  
MCV 15 pg Crenation  
MCHC 32 g/dl Target  
PLT 350000 x 103 /mm3 Hypochrome  
TP 5.4 gr/dl BasoStrip  
FIB   mg/dl Sphero  
Retic 0.2 % NRBC/199 WBC  
PUNT  
AGGR  
SED RATE   mm
Differentials:
Assessment:
What is your assessment of the hematology data?
Test % Absolute  
Point your
mouse here
to view Hematology Norms
 
SEG   11000
Band   200
Lymph   3300
Eosin   1000
Mono   0
Baso   0
Other   0
PLTest    
Toxic
change
0

Biochemical profile:
Test Value Unit  Point your
mouse here
to view Chemistry Norms
 
Test Value Unit
Sodium 148 m mol/L T. Bili 0.2 mg/dl
Potassium 3.5 m mol/L ALKP 150 u/l
Chloride 119 m mol/L ALT 120 u/l
TCO2 16 m mol/L AST   u/l
Urea 20 mg/dl LDH   u/l
Creatinine 1.1 mg/dl CK   u/l
Calcium 10.3 mg/dl GGT 2 u/l
Phosphorus 3.5 mg/dl Magnesium   mg/dl
Glucose 115 mg/dl Osmolality   mosm/L
T. Protein 6.5 g/dl Anion Gap   mosm/L
Albumin 3.1 g/dl
Globulin 3.4 g/dl
A/G ratio  

What is your assessment of the biochemical profile?

Urinalysis: Microscopic Sediment Exam:
Test Value Unit   Test Value Unit
Volume 5 ml WBC 0-2 ml
Color yellow   RBC 36162  
Transparency clear   Bacteria 0  
Specific Gravity 1.018   Epitheliel 0  
Phosphorus     Fat 0  
Protein neg mg/dl Sperm 0  
Ketones neg mg/dl CaOxalate 0  
Bilirubin neg   CaCarbonate 0  
Blood neg   TriplePhos 2 plus  
Urobili neg   Bilirubin 0 mg/dl
      Amorph 0 mg/dl
      Casts 0  
What is your assessment of the urinalysis data?
Identify the major ruleout(s) supported by this data.

Have you identified any new problems?

  If so, what are they?
List the diagnostic tests or procedures that should be performed next.

RX:

What immediate therapy would you prescribe for problems identified in Section 2?

Learning Issues:

Review the causes of PU/PD in cats and describe the mechanisms for hyperthyroidism
Review the diagnostic procedures for confirming hyperthyroidism in cats
Describe the sensitivity and specificity of diagnostic tests for feline dirofilariasis
Review the ECG and radiographic findings of thyrotoxic cardiac disease
Describe the pathophysiology of thyrotoxic cardiac diseases

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This page was last updated 10/19/07 09:51:09 AM