1 . Which one of the following abnormalities is common to both primary and secondary hypothyroidism?
Presence of thyroglobulin antibodies
Increased levels of TSH
Thyroid gland necrosis
Reduced synthesis of thyroxine
Decreased levels of TRH

2.All of the following compounds may decrease serum thryoxine levels except?
Phenobarbital
Prednisone
Sulfonamides
Estrogen
Trimethoprime/ormethaprime

3.Which one of the following is correct regarding euthyroid sick conditions?
T4 is more affected than T3
T4 is more affected than fT4
TSH is affected more than T4
Dermatological disease is a common cause
None of the above are correct

4.Which one of the following statements is correct regarding thyroid gland physiology?
The major hormone secreted is tri-iodothyronine
About 50-60% of thyroxine is bound to plasma proteins
The half life of T4 in dogs is 21 days
Thyroid hormones are made from iodinated tyrosine
Thyroxine enhances the synthesis of cholesterol

5.Regarding hypothyroidism in dogs and cats, which one of the following is correct?
The disorder is common in both species
The etiology in dogs includes immune mediated disease.
Auto-antibodies to T4 and T3 are the major etiology in dogs and cats.
Secondary hypothyroidism is common in dogs and cats.
The most common cause of hypothyroidism in cats is idiopathic atrophy.

6.All of the following are documented problems or signs of hypothyroidism in dogs except?
Facial neuropathy
Peripheral vestibular disease
Epilepsy
Myopathy
Recurrent pyoderma

7.A dermatological sign relative specific for hypothyroidism is?
Alopecia
Calcinosis cutis
Follicular hyperkeratosis
Seborrhea
Myxedema

8.Which one of the following is considered the "Gold Standard" of thyroid function tests?
T4
TSH response test
fT4
cTSH
TRH response test

9.A hormone produced by "C cells" in the thyroid gland is:
GI polypeptide
Renin
PTH
Thyroxine
Calcitonin

10.All of the following are physiologic effects of thyroid hormones except?
increase protein synthesis
increase heat production
stimulate erythropoiesis
Up regulate sympathetic nervous system
Decrease enzyme and cyclic AMP production