Endocrinology Case 1 Review Questions

1 . Diseases that primarily affect the collecting ducts create?
urine high in solutes
hyponatremia
hypercalcemia
hypertesion
hyposthenuria

2.The purpose of the MWDT is to?
stimulate release of aldosterone
decrease medullary hypetonicity
gradually increase plasma osmolality/stimulate release of ADH
confirm diagnosis of diabetes insipidus
confirm diagnosis of renal failure

3.Which one of the following is not a contraindication for MWDT?
Hypercalcemia
Azotemia
Increased ALKP
Hyperalbuminemia
Hypernatremia

4.Antidiuretic hormone is produced in?
The pars distalis
The pars intermedia
the pars nervosa
the hypothalmus
the adrenal medulla

5 . The primary effect(s) of ADH is (are):
Decrease plasma osmolality, increase urine osmolality, decrease blood pressure.
Increase plasma osmolality, decrease urine osmolality, increase heart rate
increase osmolality of plasma and urine, increase blood pressure
Decrease plasma osmolality, increase urine osmolality, increase blood pressure.
Decrease plasma and urine osmolality, increase blood pressure
Increase urine osmolality, little or no effect on plasma osmolality or blood pressure

6 . The segnment of the nephron that actively reabsorbs solutes, passively reabsords water and decreases the volume of glomerular filtrate by 60-70% is:
proximal convulated tubule
collecting ducts
ascending limb of Henle's loop
distal convulated tubule
descending limb of Henle's loop

7 . The segment of the nephron that decreases glomerular filtrate below 1.008 is:
distal convoluted tubule
proximal convoluted tubule
collecting ducts
thin segment of Henle's loop
thick segment of Henle's loop

8 . All of the following diseases cause PU/PD by altering the action of ADH except:
diabetes insipidus
hypercalcemia
hyperadrenocorticism
pyometra
diabetes mellitus

9 . The specific gravity of glomerular filtrate is approximately:
1.022
1.008-1.012
1.004
1.015
1.035

10 . Renin is secreted:
by the adrenal cortex
by the pars distalis
by the adrenal medullar
by the juxtaglomerular apparatus
by the distal convulated tubule