1 . Which one of the following is NOT an effect of insulin? Facilitates transport of glucose into cells except neurons, RBC's, intestinal mucosa, and renal tubular epithelium. Promotes glucose trapping in hepatocytes. Promotes glycogen storage in liver. Inhibits lipoprotein lipase Inhibits protein synthesis
2.All of the following are anti-inuslin or hyperglycemic hormones EXCEPT? Progesterone Vasopressin Glucagon Epinephrine Thyroxine
3.Which of the following statements is NOT correct regarding the control of insulin? Insulin release is controlled by concentration of glucose in beta cells. Certain amino acids are potent stimulators of insulin release. At a blood sugar of 50 mg/dl, insulin release should cease. At a blood glucose od 110-120 mg/dl, insulin secretion should increase. Secretin and cholecystokinin promote insulin secretion.
4.Which one of the following risk factors is most important in the development of DM in cats? Hereditary Obesity High carbohydrate diet Infection Concurrent disease
5.Which one of the following is NOT CORRECT regarding the pathophysiology of diabetic ketoacidosis? Stress hormones are an important component Underlying infection is commonly present Relative insulin resistance is present Increased activity in glycolytic pathway is a key feature Hepatic ketone production is increased
6.Which answer is INCORRECT regarding the diagnosis or laboratory findings in DKA? Urine specific gravity is usually 1.018-1.028. Hypernatremia indicates free water loss. Potassium depletion is common. Azotemia is commonly present. Hyperphosphatemia is common.
7.Which one of the following represents the best treatment for a dog with diabetic ketoacidosis, a blood glucose of 425 mg/dl, serum sodium of 134, serum potassium of 3.2, and TCO2 of 13? Regular insulin, lactated Ringers, sodium bicarbonate NPH insulin, normal saline, potassium Regular insulin, normal saline, potassium Regular insulin, normal saline, sodium bicarbonate NPH insulin, lactated Ringers, potassium
8.In the management of DKA, which one of the following statements is NOT correct? Regular insulin inhibits lipolysis and hepatic glucose production, Blood glucose should decrease by 50-100 mg/dl/hour Rapid reduction in blood glucose produces cerebral edema. A decreasing blood sugar is associated with ketone metabolism Regular insulin therapy is not stopped until the blood sugar is in the normal range.
9.Which one of the following statements best describes the Somoygi phenomenon? Hyperglycemia caused by under-dosing insulin Rebound hyperglycemia from feeding too much simple carbohydrates. Most commonly occurs 18-20 hours after insulin therapy Hyperglycemic effect caused by over-dosing insulin Hypoglycemia found 18-20 hours after insulin therapy
10.The most common form of diabetes mellitus in dogs is? Type 1 Type 2 Type 3 Insulin resistant Type 4
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