Endocrinology Case 10

Enter your name or student identification: Instructions!

1. Data Base Collection

Signalment: 9 year, M/C, DSH. Weight 17 pounds

History: Cat has a long history of eosinophilic granuloma complex and indolent ulcers. He is treated with methylprednislone acetate injections at 2.2 mg/kg every 6-8 weeks. Four weeks ago, he was started on megesterol acetate at 5 mg orally 3 times a week. During the past week, the owner has noticed a marked increase in appetite and thirst. The litter box seems very wet. There is no vomiting, diarrhea, coughing or sneezing. The cat is vaccinated every 2 years with polyvalent vaccine and every 3 years for rabies.

Physical Examination: T. 102.4 F, HR 160, RR 30, MM pink, CRT <2.0 seconds. Lymph nodes are normal, oral cavity is normal, chest auscultation is negative, abdominal palpation is negative and there is no evidence of dehydration.

Diagnostic Plan: Using the POVMR format, identify the problems and formulate a diagnostic plan for this case.

2. Problem Identification

A. List the problems you have observed.

No.

     Problem

1 .

2 .

3 .

4 .

5 .

6 .

7 .

8 .

9 .

10 .

B. Of the problems you have identified, which is (are) the most important to manage?

3. Plan Formulation

A. DX: List ruleouts for the problems you identified in Step 2.

Problem
No.

     Ruleout(s)

1 .

2 .

3 .

4 .

5 .

6 .

7 .

8 .

9 .

10 .

B. List those diagnostic procedures that will be most cost-effective.

1 .  2 . 

3 .  4 . 

5 .  6 . 

7 .  8 . 

9 .  10 . 

4. Assessment & Follow-up

Analyze the initial database results.

Hematology: RBC Morphology:
Test Value Unit
Point your
mouse here
to view Hematology Norms
 
Test Value
WBC 8.5 x 103 /mm3  Normal  
RBC 7.2 x 106 /mm3  Rouleaux none
HGB 12 g/dl Polychrome none
PCV 40 % Aniso none
MCV 44 fl Poik none
MCV 16 pg Crenation none
MCHC 34 g/dl Target none
PLT 325 x 103 /mm3 Hypochrome none
TP 7.6 g/dl BasoStip none
FIB   mg/dl Sphero none
Retic 0 % NRBC/100 WBC none
PUNT  
AGGR  
SED RATE   mm
Differentials:
Assessment:
What is your assessment of the hematology data?
Test % Absolute  
Point your
mouse here
to view Hematology Norms
 
SEG   4000
Band   200
Lymph   2300
Eosin   1500
Mono   500
Baso   0
Other    
PLTest    
Toxic
change
none

Biochemical profile:
Test Value Unit  Point your
mouse here
to view Chemistry Norms
 
Test Value Unit
Sodium 150 m mol/L T. Bili 0 mg/dl
Potassium 3.9 m mol/L ALKP 150 u/l
Chloride 125 m mol/L ALT 64 u/l
TCO2 17 m mol/L AST   u/l
Urea 20 mg/dl LDH   u/l
Creatinine 1.3 mg/dl CK   u/l
Calcium 10.9 mg/dl GGT   u/l
Phosphorus 3.8 mg/dl Magnesium   mg/dl
Glucose 210 mg/dl Osmolality   mosm/L
T. Protein 6.8 g/dl Anion Gap   mosm/L
Albumin 3.6 g/dl
Globulin 3.2 g/dl
A/G ratio  

What is your assessment of the biochemical profile?

Urinalysis: Microscopic Sediment Exam:
Test Value Unit   Test Value Unit
Volume 5 ml WBC 0-2 ml
Color Dark yellow   RBC 0-2  
Transparency Opague   Bacteria 0  
Specific Gravity 1.041   Epitheliel 0-3  
Phosphorus     Fat    
Protein 0 mg/dl Sperm    
Ketones 0 mg/dl CaOxalate    
Bilirubin 0   CaCarbonate    
Blood 0   TriplePhos 3+  
Glucose 2+   Bilirubin   mg/dl
      Amorph moderate mg/dl
      Casts 0  
What is your assessment of the urinalysis data?
Identify the major ruleout(s) supported by this data.

Have you identified any new problems?

  If so, what are they?
List the diagnostic tests or procedures that should be performed next.

RX:

What immediate therapy would you prescribe for problems identified in Section 2?

Learning Issues:

Compare the etiology and pancreatitic lesions found in diabetic dogs and cats.
Describe the consequences of poorly controlled diabetes mellitus in dogs and cats.
Describe the pathophysiology of IDDM, NIDDM and transient DM
Compare the use of oral hypoglycemic agents in dogs and cats and describe their mechanisms of action.
Review the types of insulin used in cats and ways to monitor glycemic control in this species.

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This page was last updated 10/19/07 09:51:09 AM