Endocrinology Case 10 Review Questions

1 . Which one of the following groups of findings is CORRECT regarding diabetes mellitus in dogs and cats?
Cat: More common in females, breed specific, >7 years old.
Dog: More common in males, breed specificity possible, >7 years
Cat: More common in males, not breed specific, >7 years old.
Dog: More common in females, no breed specificity, <7 years
None of the above

2.Considering the pathogenesis of diabetes mellitus in dogs and cats, which one of the following is CORRECT?
The most common histopathological lesion in cats is islet amyloidosis
Most dogs have NIDDM
Most cats have NIDDM
Transient DM is more common in dogs than cats
Immune-mediated destruction of islet cells is the common lesion in cats.

3.Regrading the consequences of DM in dogs and cats, which one of the following is CORECT?
Cataracts more common in cats
Neuropathies more common in dogs
Diabetic retinopathy common in both species
Diabetic nephropathy more common in cats
Pancreatitis more common in cats

4.Insulin resistence in dogs or cats has been documented in the following diseases EXCEPT?
Hypothyroidism
Hyperthyroidism
Hyperadrenocorticism
Acromegaly
Pyometra

5.Which one of the following is the best way to assess glycemic control in dogs or cats receiving insulin therapy?
Assessing urine glucose just before insulin therapy
Assessing blood glucose before morning insulin therapy
24 hour serial blood glucose curves
Assessing blood glucose 12 and 24 hours after insulin therapy
Assessing urine glucose 8, 12 and 24 hours after insulin therapy

6.Which one of the following is most often responsible for erronous results on serial blood glucose curves in cats?
Failure to eat during test
Variable results from glucometers
Inadequate size of blood samples
Stress induced hyperglycemia
Patient variability

7.For initial insulin therapy in diabetic cats, which one of the following is NOT Correct?
A long acting insulin such as Ultralente is a good choice
Lente insulin is satisfactory in many cats
The absorption of Ultralente may be slow in some diabetic cats.
Intermediate insulin (NPH) works best in cats
Initially insulin is given once a day.

8.Which one of the following is CORRECT regarding oral hypoglycemic agents (glipizide) in diabetic cats?
They directly stimulate insulin secretion from beta cells
They desensitize peripheral insulin receptors
They increase hepatic glycogenolysis
Azotemia is a common side effect
They are superior to insulin

9.Diabetic dogs and cats are polyphagic despite hyperglycemia. Which one of the following is the correct reason for this finding?
Increased presence of fatty acids stimulates the appetite center
Cortisol release stimulates the appetite center
Glucose inhibition of the satiety center is decreased
Decreased hepatic gluconeogenesis is the explanation
The satiety center is inhibited by triglycerides

10.The best diet for treating a diabetic dog or cat is one that contains?
High fiber, restricted protein, restricted fat
Low fiber, moderate protein, restricted fat
Moderate fiber, low protein, and low fat
High complex carbohydrates, high fiber, moderate fat and protein
Restricted fat, moderate protein

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