Histology by Charlotte L. Ownby, PhD.  Links to beginning of Histology web site.

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Histology
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Diagram of Female Reproductive System

System
diagram

Back to Oviducts (Uterine tubes) Proceed to Vagina

The Uterus

Functions
  1. serves to receive the sperm in mares
  2. transports sperm from site of deposition to uterine tubes for fertilization
  3. provides suitable environment for 
    a. implantation of the embryo
    b. nourishment of the embryo & fetus during pregnancy
  4. provides mechanical protection of the fetus
  5. expels the mature fetus at the end of pregnancy

The diagram to the right shows the parts of the uterus of a sow.    

Other views

Point (don't click) on the animals in the list below.

Notice the similarities and differences in domestic animals:

  1. uterine horns
  2. body
  3. cervix 

pig
cow

dog
horse
human

gross anatomy: click click here
other domestic species: click here

Histology 

In the fundus and body of the uterus, the wall is divided into the 
  1. endometrium = tunica mucosa and tunica submucosa
  2. myometrium = tunica muscularis
  3. perimetrium= tunica serosa   

These are terms specific to the uterus that apply to the typical tunics of a tubular organ. 

Click on the image at the right to view the labeled histological images.

 

The 4 images show the histological details of the tunics of the uterus.

The endometrium  comprises the tunica mucosa and the tunica submucosa of the uterus. 

In the tunica mucosa the lamina epithelialis is usually simple columnar except in the sow and ruminants where it may be pseudostratified columnar. 

The lamina propria consists of loose connective tissue full of neutrophils and lymphocytes.  It blends with the underlying tunica submucosa since there is no lamina muscularis mucosae in the entire female reproductive tract. 

Uterine glands are simple or branched tubular glands located in the lamina propria-tunica submucosa. Some regions of the endometrium in ruminants are void of glands and are highly vascular.  It is in these regions, called caruncles, that contacts between the uterus and the extraembryonic membranes are made.

Click on the image below to view the histological images.

The myometrium is the tunica muscularis of the uterus.  It is composed of a thick inner circular layer and a thinner outer longitudinal layer of smooth muscle.  The region in between the two layers of smooth muscle contains large blood vessels.   The perimetrium is the tunica serosa of the uterus. It has the typical composition of  loose connective tissue, but contains a large number of lymphatic vessels.

 

The stratum vasculare is a layer of large blood vessels located between the inner and outer layers of smooth muscle of the myometrium.

In the sow the stratum vasculare is indistinct and in the cow it may be located in the outer half of the circular muscle layer. 

Click on the image at the right to view the histological images.

Species differences

In the bitch, queen, and mare the epithelium of the tunica mucosa is simple cuboidal or columnar.  
In ruminants and the sow the epithelium is stratified or pseudostratified.  

Uterine glands may be coiled in ruminants, the sow, and the mare. 

 

Glands

Uterine glands are simple or branched tubular glands, and may be coiled distally. Distal portions of the glands are in the lamina propria/tunica submucosa. The glands secrete mucus, glycogen, proteins, and lipids. The remainder of the endometrial tissue is loose connective tissue.

Click on the image at the right to view histological images at 2 magnification levels.

 

 

Quick Checks:
1. The divisions of the wall of the uterus are analagous to the tunics of any tubular organ.  Which one of the following analogies is correct?:
endometrium = tunica serosa; myometrium = tunica muscularis; perimetrium = tunica mucosa
endometrium = tunica epithelialis; myometrium = tunica mucosa; perimetrium = tunica adventitia
endometrium = tunica mucosa-submucosa; myometrium = tunica muscularis; perimetrium = tunica serosa

2. The glands in the uterus secrete the following:
progesterone
estrogen
mucus, glycogen, proteins and lipids

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This page was last updated 10/19/07 09:53:56 AM